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Betaine Anhydrous

The History & Background of Betaine Anhydrous

Betaine anhydrous is a vitamin obtained from choline. Choline is a macro nutrient that’s important for liver and nerve function, development of normal brain, movement of muscle, supporting energy levels and maintaining a healthy metabolism. The said ingredient occurs naturally in the body, and can also be found in foods such as sweet beets, spinach, cereal grains, seafood, sweet potato, beef and wine. It is also used as an ingredient in toothpaste to reduce dry mouth. It has a molecular weight of 117.15.

Betaine Anhydrous is approved for treatment of Homocysteine or chemical of high urine levels in people with certain inherited disorders. Homocysteine is an amino acid produced by the body and also is in your blood. When it is on high level, it is linked with heart disease, weak bones (osteoporosis, rickets, etc.), skeletal problems, and eye problems (cataract, color blindness etc.).

Betaine Anhydrous is also known by the several names such as Glycine, Glycine betaine, Trimethylbetaine, Trimethylglycocoll, Abromine, Glycylbetaine, Oxyneurine, Trimethylglycine (TMG), Methanaminium1-carboxy-N,N,N-trimethyl-, inner salt, 2-(Trimethylammonio) ethanoic acid, hydroxide, inner salt, (Carboxymethyl) trimethylammonium hydroxide inner salt and Trimethylammonioacetate.

Use in Supplements

There are even more motivating reasons why we use Betaine Anhydrous as a supplement, these will include:

  • Increased power output
  • Increased capacity to perform anaerobic work
  • Increased energy levels
  • Promotes cellular hydration (similar to creatine)
  • May reduce LDL cholesterol/blood lipids
  • May help reduce body-fat tissue (needs more conclusive research)

Common Dosing

Recommended dosing of the ingredient starts with a once-daily dose of 2.5 grams.

If desired, the dose may be increased to 5 grams split into two doses throughout the day.

Products Containing Betaine Anhydrous

Nutricost Betaine Anhydrous Trimethylglycine (TMG) Powder 500 GramsNutricost Betaine Anhydrous Trimethylglycine (TMG) Powder 
Price: $14.95
Contains: 500 Grams of Betaine Anhydrous
AVG Review:4.4 stars on Amazon
Read More [...]

Betaine Anhydrous is a derivative of choline and is an important nutrient. It is also known as trimethylglycine (TMG). The name Betaine Anhydrous is derived from sugar beets, the vegetable in which it was first identified. Its availability is not limited to sugar beets though, as it can be found in many different dietary sources.

Pure Betaine Anhydrous Trimethylglycine (TMG) Powder by Muscle Feast (300 grams)

Pure Betaine Anhydrous Trimethylglycine (TMG) Powder by Muscle Feast

Price: $14.99 ($0.05 / Gram)
Contains: 300 grams of Betaine Anhydrous
AVG Review:4.4 stars on Amazon
Read More [...]

Pure Lab tested betaine anhydrous


LiveLong Nutrition Betaine Supplements, 3.5 Ounce

LiveLong Nutrition Betaine Supplements
Price: $16.14 ($4.61 / Ounce)
Contains: 100 grams (3.5oz) of Betaine Anhydrous
AVG Review: 3.8 stars on Amazon
Read More [...]


Betaine anhydrous supports healthy body weight, mood support, homocysteine protection. Mood support. Supports healthy body weight.

Potential Side Effects of Betaine Anhydrous

Fortunately, Betaine Anhydrous has limited side effects with minimal doses. However, all consumers should follow recommendations and guidelines. It needs to be used properly in order to reduce the chance of possible side effects.

While side effects are rare, they can still occur in some people. The most common side effects are nausea, gastrointestinal displeasure and even diarrhea. It may increase blood levels and cholesterol for some people. If itching, heavy breathing, rashes or swelling in hands or faces occur, you must immediately discontinue use of the product. If symptoms persist, consult a doctor or physician about it.

There are consumers who should not supplement Betaine Anhydrous such as those who have kidney disease, cardiovascular disease, who are dealing with homocystinuria and diabetics. Pregnant and breastfeeding may consult a physician prior to Betaine Anhydrous operation.


Q: I’ve heard betaine should be taken on an empty stomach, is this true?

A: This is likely due to the rare occurrence of stomach distress that may occur after ingesting betaine anhydrous; it is actually absorbed fine with or without a meal.

Q: How long does it usually take for me to notice the effects of betaine anhydrous?

A: Betaine anhydrous should start to gain effectiveness after the first week or two of use. Most of the benefits are rather acute though.

Q: Can betaine anhydrous hydrate cells?

A: Yes. Betaine has an affinity for water, and therefore, can increase the hydration and maintenance of hydration in cells.


Studies show that Betaine Anhydrous is a versatile vitamin that is used by the body for an extensive variety of physiological motivation. Betaine Anhydrous for animals support liver health and it has been suggested to promote lean mass. For humans, it is the maintenance of intestinal function, kidney health and serves as an antioxidant. It is also noted that the said ingredient increases appetite and improve digestive productivity.

Betaine Anhydrous is potentiated in the existence of choline (its precursor), folic acid, and vitamins B-6 and B-12. Fortunately, it can be used as a substitute for methionine and choline chloride.

Final Review of Betaine Anhydrous

I am amazed by the benefits that are possible from a single ingredient, it supports overall health. Betaine Anhydrous is a powerhouse ingredient that has more healthy effects, good development to our body functions and it works very well.