The History & Background of Tomatidine
Tomatidine comes from the tomato plant. Tomatoes are known for its famous and influential compound which is the antioxidant lycopene. Lycopene is well-known for its ability to fight oxidative stress, limits the spread of radicals, and even helps fight different types of cancer while tomato dice is just starting to gain popularity for the many benefits it offers and this includes good muscle-building properties.
Tomatidine is classified as a steroidal alkaloid from the chemical breakdown of Tomatine along with 2 moles of D-glucose. Sterol alkaloids are sterols commonly found in plants, animals, and fungus that are popularly known as cholesterol.
Tomatidine was just recently discovered compared to lycopene. Studies are still ongoing for its many undiscovered health benefits.
Use in Supplements
Tomatidine isn’t just healthy for the body; it also combats muscular atrophy and weakness. The latest research on tomatidine shows that it is also useful in building muscles. Tomatidine has also been found to help increase skeletal muscle mTORC1 signaling, which stimulates muscle growth and reduces muscle wasting. It also increases one’s muscular capacity of strength and exercise, promotes skeletal muscle hypertrophy, lessens skeletal muscle wasting, and enhances recovery.
Tomatidine has many desirable benefits that improve health and lifespan, and it is not just for muscle building. It is currently undergoing further research for its potential cancer-fighting and antioxidant properties, much like the ingredient Lycopene.
Common Dosing
Tomatidine is relatively new to the bodybuilding world, and a precise cut ideal dosage has yet to be established. If we look at what the research shows, it implies that splitting the dose into 1-4 servings per day seems to be the most favorable dosage for tomatidine. For more specific information regarding the dosage, the Journal of Clinical Pharmacy Standards gave a clearer tomatidine dosage. For a 150 lb man to see visible results, he needs to dose himself between 90-110 mg daily.
Products Containing Tomatidine
Lycopene 30 mg – All Natural Prostate Supplements for Men. Promotes Heart Health. Menopause and Bone Health Support. Non GMO – by Jiva BotanicalsPotential Side Effects of Tomatidine
From the recent research performed, Tomatidine is said to have no adverse effects when consumed in concentrated doses. Tomatidine is considered safe because it is a natural ingredient. However, as supplemental levels are more than what we usually consume from tomatoes, there is still a bit of hesitation concerning to long term, high concentrations of Tomatidine. In human studies using Tomatine, little to non-existent side effects were reported. In animal studies, oral consumption of LD50 (the amount of an ingested substance that kills 50% of a test sample) is around 500mg/ which is most likely similar to Tomatidine. Side effects experienced in excess consumption of Tomatine will also be the same for Tomatidine, which includes vomiting, diarrhea, abdominal pain, drowsiness, confusion, weakness, and depression.
FAQs
My Tomatidine arrived after days and was left at room temperature. Is the product still good acceptable to use?
Most of our product is solid. The product can be stored for up to 3 months under the storage condition. For long-term storage, most of our products are refrigerated or frozen. Short periods at higher temperatures than those recommended (periods < 1 week), such as during shipping, will not significantly affect the product life or efficacy. Storage condition of Tomatidine is stated on the product COA.
Does Tomatidine have any other names?
Suvorexant; Tomatidine
How should I dissolve the Tomatidine I purchased?
You can dissolve your Tomatidine in the solvent stated in solubility information in our product web page. 10 mM in DMSO
Studies
A study was conducted on the effectiveness of tomatidine in enhancing the lifespan and healthspan in C.elegans through mitophagy induction via the SKN-1/Nrf2 pathway. Tomatidine inhibits age-related skeletal muscle atrophy in mice. C.elegans was used in the study, an animal model of aging, which shares many major longevity pathways with mammals. Microarray, imaging, and behavioral analyses reveal that tomatidine maintains mitochondrial homeostasis by modulating mitochondrial biogenesis and PINK-1/DCT-1-dependent mitophagy. Mechanistically, tomatidine induces mitochondrial hormesis by mildly inducing ROS production, which in turn activates the SKN-1/Nrf2 pathway and possibly other cellular antioxidant response pathways, followed by increased mitophagy. This mechanism occurs in C. elegans, primary rat neurons, and human cells. The data suggest that tomatidine may delay some physiological aspects of aging, and can be a way to new approaches for pharmacological interventions for the disease of aging.
Some researchers carried out in-vitro and animal studies. They used to feed that contained 0.05% tomatidine, which is about 0.5 g for the human equivalent of this dose. It lasted for nine weeks. And to make it clear, this study was financed by the researchers’ university and the American government and not by the supplements industry. In the in-vitro studies, muscle cells exposed to tomatidine formed muscle fibers faster than the usual. More mitochondria were created, and more protein structure was also produced. Tomatidine activated the anabolic signaling molecule Akt and SK6, and the muscle cells were induced to produce more IGF-1 and PGC-1-alpha. Tomatidine being added to the feed stimulated muscle growth in both young and older mice. It made the mice a bit stronger, and it also boosted the capacity of their endurance. Tomatidine supplementation increased lean body mass and, at the same time, inhibited growth in fat mass for the mice. Tomatidine was also discovered to have inhibited muscle breakdown during fasting.
Final Review of Tomatidine
Tomatidine gives various health benefits to the human body. Almost everyone could use this ingredient, but I will most likely recommend this for people who want to build their muscles for its excellent muscle-building properties naturally. Being a natural ingredient coming from tomatoes, it is proven to be safe and effective. It has also been recently found to be a potential cancer-fighter. Tomatidine has so much to offer, and it is definitely worth the try.
References :
https://blog.priceplow.com/tomatidine
https://www.mrsupplement.com.au/tomatidine-for-muscle-building
One reply on “Tomatidine”
I saw tomatidine at $120.00 wy your $8.50