Divanil (Nettle Root)

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The History & Background of 3,4-Divanillyltetrahydrofuran


Type: Anabolic Compound

Potency: 8/10




3, 4-Divanillyltetrahydrofuran is a lignan found in a Urtica dioica (stinging nettle) subspecies. This same compound may also be found in other lignan-containing plant sources such as Linum usitatissimum (flax seed).

The compound has been found to occupy binding sites of sex hormone-binding globulin (SHBG), thereby reducing the ability of SHBG to bind additional steroid hormones such as estrogens and androgens, mostly testosterone and estradiol. Certain extracts of stinging nettle are therefore used by some bodybuilders in an effort to increase free testosterone.

Use in Supplements

Divanil binds with very high affinity to sex hormone binding globulin (SHBG), which will increase the concentration of free testosterone;  as a result, giving the athlete all the wonderful things more testosterone will give.  Studies have shown, Divanil does bind to SHBG, so, thereotically, your free testosterone levels will rise even if your total testosterone stays the same.   In simple terms, Divanil is an incredible weapon to help you raise your free testoerone levels without suppressing your LH.

Common Dosing

A solid dosage is around 600mg a day both on cycle and definitely during post cycle therapy or Typical Stinging Nettle extract dosage is somewhere around 1.5 g daily divided into 500 mg doses. In studies evaluating its efficiency for diabetes, doses up to 100 mg/kg are used. Manufacturers typically recommend doses between 600 mg to 1.500 mg per day.

Products Containing 3,4-Divanillyltetrahydrofuran

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Potential Side Effects of 3,4-Divanillyltetrahydrofuran

The main side effect of using Divanil is due to its effects on boosting testosterone levels, which would convert into estrogen; hence, those who are sensitive to estrogenic side effects may, in rare cases, have to watch for any light estrogen related issues.  However, when used as part of a stack with other supplements this phenomenon will balance itself out and shouldn't be a concern for the athlete.   Otherwise, Divanil is a natural root and is safe to use.


Hey guys…picking some of this up in bulk…whats the nomal dosing? AX's blend is proprietary, but I'm assuming about 1.2grams a day is what it is usually dosed at?

The original Activate was dosed at 400mg per cap @ 4 caps per serving so 1.6 grams per day. Some people might have gone up to 6 caps 2.4 grams

 Is there hard evidence this stuff actually increases testosterone?

I do believe it works, although in the absence of clinical studies, I cannot prove so, even with my own bloodwork showing that it worked for me individually.


It’s been proven in countless studies that higher levels of testosterone produces greater muscle mass, less body fat, greater strength, and, of course, stronger libido.  For an athlete, Divanil has an effects on SHBG, which increases free testosterone.  In addition, studies have also shown it will help boost LH as well, which makes it a tremendous addition to a post cycle therapy (PCT) when LH levels are suppressed due to an anabolic steroid cycle.

Final Review of 3,4-Divanillyltetrahydrofuran

Our final review in this ingredient is that good for athletes. It will make you incredible specially to the bodybuilders.

And because of that, I recommend Brickhouse™ V2. Brickhouse™ V2 can promote faster muscle recovery, faster muscle repair, lean mass gains, body fat reduction and strength gains.









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