Ingredients: Agmatine Sulfate

Ingredients: Agmatine Sulfate

The History & Background of Agmatine Sulfate

Type: Nootropic

Potency: 8/10

Agmatine Sulfate, also known as Agmatine is a bodybuilding supplement (typically labeled a nitric oxide booster) and is known for enhancing mind-muscle association as well as contractive endeavors of muscles.

Agmatine Sulfate was first introduced to the public in the year 1994. This potential solid neurotransmitter helps coordinate compressions and can thus improve adequacy of activities. In addition, Agmatine also helps in releasing the luteinizing hormone or Gonadotropin. This hormone is responsible for expanding luteinizing hormone levels. Luteinizing hormone fortifies male leydig cells to create testosterone and is produced in the human body from a decarboxylation and transformation of Arginine to Agmatine.

Use in Supplements

The key benefits of Agmatine Sulfate are godlike pumps, improved endurance, increased vascularity and better overall athletic performance.

A few of the other benefits to bodybuilders you may experience are:

  • Increases in Growth Hormone Output
  • Increased IGF-1 Output
  • Increased Luetenizing hormone Output
  • Better Insulin Sensitivity
  • Increased levels of Nitric Oxide
  • Antioxidant
  • Builds Muscle & Burns Fat
  • May even reduce pain

Common Dosing

Due to limited research on Agmatine Sulfate, there is no approved recommended dosage of the supplement. However, it is commonly taken up to 750 mg.

Dosages of Agmatine may vary according to person’s weight:

  • 120 lbs – 87 to 349 mg per day
  • 140 lbs – 102 to 407 mg per day
  • 160 lbs – 116 to 465 mg per day
  • 180 lbs – 131 to 523 mg per day
  • 200 lbs – 145 to 581 mg per day
  • 220 lbs – 160 to 640 mg per day
  • 240 lbs – 175 to 698 mg per day

Products Containing Agmatine Sulfate

Potential Side Effects of Agmatine Sulfate

Thankfully, Agmatine is moderately safe to be consumed even in high levels and appears to have low lethality in cells. In the primary clinical trial of Agmatine, there were a few reactions and a small number of individuals reported their experience of gentle sickness.


Is there any common food product that contains Agmatine?

Agmatine is basically a bacterial byproduct and is therefore present in fermented food products such as beer and wine. It is also found in instant coffee. The amount of agmatine present in these products is extremely low.

The amount of agmatine found in bodybuilding supplements is significantly higher as compared to the amount present in these food products.

Are Agmatine and Arginine exactly the same?

No. Although Argmatine is a derivative of l-arginine, they do not provide the same benefits.  Arginine is important for the body as it helps the body perform many important functions. However, agmatine has its own benefits that arginine fails to provide.

In addition, arginine can directly convert into nitric oxide but agmatine cannot.  In spite of this difference, agmatine is still able to impact muscle pumps positively through other physiological methods.

How much Agmatine can you consume per day?

Although research shows that agmatine is moderately non-toxic, limited research has been conducted on consumption of dosages above 2.6 grams/day. Due to this reason, it is recommended to avoid over-dosing.

Does Agmatine help in alcohol withdrawal?

The consumption of this supplement appears to satisfy the symptoms related to alcohol withdrawal. These symptoms include shakes and anxiety.

Are there any dangerous Agmatine combinations?

Research shows that yohimbine, l-citrulline, l-arginine, creatine, and D-aspartic acid should not be consumed with agmatine as they hinder its effectiveness.

Is there any supplement that can be combined with Agmatine to increase benefits?

Hormone supplements can be consumed along with Agmatine to enhance performance, improve stamina, and speed up recovery. Consumption of carbohydrates with Agmatine also increases benefits as it helps boost glycogen resynthesis.


Research into Agmatine uncovers a possibility to enhance the side effects identified with neuropathic torment, and the capacity to help with the treatment of medication enslavement. Agmatine additionally administers nitric oxide (NO) union, and also attempts to appropriately direct cell vitality by managing polyamine metabolic capacity. This makes Agmatine sulfate a well-known pump-instigating supplement decision.

Agmatine has an extraordinary remedial capability to treat different illnesses. Late clinical investigations have just demonstrated that oral Agmatine sulfate consumed for 3 weeks gives a safe and more successful treatment for neuropathic torment. These examinations have introduced the utilization of dietary Agmatine as a nutraceutical. In any case, keeping in mind the data lack, appraisal of long haul wellbeing of oral Agmatine treatment is presently plainly required. The creators of this report attempted to survey their own wellbeing status amid continuous utilization of high measurements of oral Agmatine over a time of 4-5 years.

Daily dosage of 2.67 g Agmatine sulfate was embodied in gelatin cases; the regimen comprised of six cases that were consumed every day, each containing 445 mg, three in the morning and three at night after suppers. Clinical follow-up comprised of intermittent physical examinations and research center blood and pee investigations. All estimations up to this point stayed inside ordinary esteems and great general wellbeing status was managed all through the examination time frame, up to 5 years. This contextual analysis appeared out of the blue and it suggested that high measurements of Agmatine might be expended for no less than 5 years without proof of any unfriendly impacts. These underlying discoveries are profoundly vital as these give huge confirmation to the broadened, long haul wellbeing of a high everyday consumption of dietary Agmatine.

Final Review of Agmatine Sulfate

Agmatine has amazing potential benefits and can be used in the treatment of a few antagonistic wellbeing conditions; for example, hypertension, nervousness, stress, and liquor withdrawal side effects. Furthermore, it can be an awesome torment reliever, particularly when utilized with opioids. However, it is recommended that you list down all the benefits and side effects before making a final decision regarding consumption and dosages of this supplement.


Staff, Nootriment Editorial. “Agmatine Sulfate Review, Benefits, Side Effects Doses.” Nootriment – Health Supplement Reviews and Research, 13 Mar. 2018, “Agmatine – Scientific Review on Usage, Dosage, Side Effects.”,, 14 June 2018,

Shaw, Steve. “Ultimate Guide to Agmatine: Benefits, Side Effects & Dosages.” Tiger Fitness Bodybuilding & Workout Supplements, Whey Protein Powder, Tiger Fitness Inc, 25 June 2018,

Gilad, G M, and V H Gilad. “Long-Term (5 Years), High Daily Dosage of Dietary Agmatine–Evidence of Safety: a Case Report.” Advances in Pediatrics., U.S. National Library of Medicine, Nov. 2014,

Sources: 2020