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Non-GMO and Gluten Free.

Uses tinted glasses which is more eco-friendly and offers a greater moisture barrier against moisture and oxygen, which helps protect nutrient viability.

Designs for Health is the physician’s choice for top quality professional strength supplements since 1989.

Manufacturer ensures all products are based on the most recent research and use the highest quality raw ingredients.

GMP (Good Manufacturing Practices) Certification.


The product’s official website and Amazon do not indicate information about money-back guarantee.

According to its creator Designs for Health, Digestzymes is comprised of a proprietary blend of digestive enzymes along with betaine HCl to support the optimal digestion of proteins, fats, and carbohydrates. 

Considering a lot of products that also focus on enhancing digestive health, what makes this supplement different and could we really trust it to deliver effective results?

In this review, we will go through the product’s ingredients that play a vital role in targeting any digestive issue, its advantages and disadvantages, as well as a few customer’s feedback.


Digestzymes Ingredients Label

Betaine HCl: promotes production of additional hydrochloric acid in the stomach, which aids digestion. It assists in the absorption of B12, calcium, iron and proteins. (Enzymedica)

GastroENZ proprietary blend:

  • Ox Bile Extract: helps in relieving the health issues faced by people who are suffering from deficiency of bile salts. (Titan Biotech Ltd.)
  • Peptidase (DPPIV): a critical enzyme that regulates a wide variety of physiological processes including eating, digestion, immune function, pain perception, growth, infection, and many others. (The Great Plans Laboratory, Inc.)
  • Amylases: responsible for the breaking of the bonds in starches, polysaccharides, and complex carbohydrates into easier to absorb simple sugars. (Integrative Therapeutics)
  • Pepsin: principal enzyme involved in protein digestion. (NCBI)
  • Proteases: responsible for the primary breakdown of proteins and polypeptides from animals and plants and for proline dipeptides from gluten and casein. (Integrative Therapeutics)
  • Glucoamylase: accountable for breaking off long chain carbohydrates or starches into sugar that will afterwards be used as fuel by the body. (World of Enzymes and Probiotics)
  • Lactase: needed for a specific biochemical reaction in the body. (WebMD)
  • Invertase: separates sucrose into its main components, fructose and glucose. (World of Enzymes and Probiotics)
  • Lipase: necessary for the full digestion of fats to their smaller fatty acid components. (Integrative Therapeutics)


While digestive enzymes help our body to easily break down foods and absorb nutrients; when taken as a supplement, the following potential side effects may occur:

  • nausea
  • diarrhea
  • abdominal cramping
  • headache
  • neck pain
  • nasal congestion
  • swelling of the legs and feet
  • rash
  • dizziness
  • low blood sugar (hypoglycemia)
  • high blood sugar (hyperglycemia)
  • diabetes mellitus exacerbation
  • gas (flatulence)
  • indigestion
  • biliary tract stones
  • abnormal feces
  • fluid in the gallbladder
  • renal cyst
  • viral infection
  • asthma
  • inflammation of the stomach (gastritis)
  • muscle spasm

Please note that a typical user may or may not experience these results. Also, this is not a complete list of all possible side effects. In case an unusual reaction occurs, please check with your physician for additional information

BENEFITS OF Digestzymes

Based on Amazon’s sales page for this product, Digestzymes generally supports nutrient absorption and digestive health, and here are the specific benefits you can get from the supplement:

  • Promote optimal digestion – Digestzyme is comprised of a proprietary blend of digestive enzymes along with betaine HCl to support optimal digestion of proteins, fats, and carbohydrates.
  • Take before meals – The use of Digestzyme before meals may be helpful for those experiencing occasional gas and bloating after eating, constipation, or a feeling of fullness after eating only a small quantity of food.
  • Synergistic Enzyme Blend – Contains protease DPP IV (dipeptidyl peptidase IV), which aids in the breakdown of casomorphin (from casein) and gluteomorphin (from gluten). The enzyme lactase helps break down the dairy sugar lactose.


Now that we have gone through the potential side effects and specific benefits of Digestzymes, it’s also important for us to consider what its customers have to say prior to making that big jump in buying the product.

Here are some customers’ testimonials:

This product has the right enzyme that allows our daughter to now eat eggs.
She did not make her own enzyme, so this product gives that to her.
We were just told that she was allergic to the protein in eggs.
We tried this product, and now we know!

– B.H.

Once I have a product I like, I don’t like to have to leave home to purchase it. Ordering on line is easy and I receive
the product(s) in days. I take various supplements and always seem to run out before I think. You guys safe
me where I don’t have to go without.

– Michelle M.

I suffer with digestive issues like so many people do. I try to avoid those pesky food items that cause the most grief but in reality you can’t eliminate them all. So I chose to use these particular enzyme supplements. I find it certainly is helpful for me. The real test was when I ran out and not long after my issues were front and center, ugh!!

– Sadie Kane

I’ve purchased this from Amazon for years. I got GI issues after taking this bottle. I just smelled inside the bottle, encountered a very bad smell & realized they’d gone bad. I just purchased a bottle somewhere else today and DID NOT encounter the same bad smell. When I went to return the bad bottle on Amazon, I was within the 30 days of the “return policy” but was told they aren’t returnable. I definitely won’t buy any more supplements on Amazon. VERY DISAPPOINTED.

– Sam

Most of the users have shared their positive experiences not only with the supplement but as well as its trouble-free ordering process.

Although one critical review states that the customer had experienced the capsules having a very bad and unusual smell, Amazon.com still shows a total of 92 customer reviews as of this writing and the product averages a score of 4.5 out of 5 stars.


Based on this article, we’ve learned that Digestzymes is a great supplement and has proven to be a successful product in achieving its goal in terms of promoting healthy digestion.

Ingredients-wise, all components play a vital role in ensuring that the body gets a sufficient amount of acid/enzymes for it to easily digest the food we eat and absorb the nutrients.

Furthermore, the product has received a lot of positive customer feedback which says a lot about the potency of the formula.


If you want to buy Digestzymes online, you can get it on Amazon. The current price is $67.40 for a total of $180 capsules. You can also save 5% by using the link below:


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