What is the Best SERM?

When it comes to pulling off an ideal post cycle therapy or PCT after cycling with anabolic steroids and prohormones, having a reliable selective estrogen receptor modulator (SERM) in your arsenal is one of the best ways to do just that.

But the thing is with so many SERM’s that are commercially available these days, picking the one that will suit your PCT needs can be rather tricky. So how about we have a quick rundown on the best SERM options that you can go for to really get the job done in terms of PCT?

SERM 101

At its simplest, selective estrogen receptor modulators or SERM’s are recently developed androgen receptor ligands that help bring back the ideal testosterone levels when taken in recommended doses. They basically work by occupying the space that is usually reserved for estrogen receptors inside the cells of the body.

When a SERM has completely occupied an estrogen receptor inside a cell, estrogen won’t be able to attach to it anymore and send its signals, which helps the hypothalamic pituitary testicular axis (HPTA) to pick up the pace on bringing back the ideal testosterone levels in the system.

Besides staving off the adverse effects of having too much estrogen in the body after cycling with prohormones and anabolic steroids like losing the gains that you’ve worked really hard for due to increased water retention, developing bitch tits or gynecomastia as well as sailing blood pressure levels, using a SERM also boosts your post cycle therapy success.

Now we’ve got that covered, let’s start walking through the best SERM’s that you can use for your PCT needs according to most bodybuilders these days…

Best SERM Pick #3: Clomid

Known generically as Clomiphene citrate, Clomid was primarily designed to promote ovulation among women who are going through irregular cycles, which can be a key factor in terms of infertility.

Clomid works by directly influencing the estrogen receptors that are found in the hypothalamus to release more luteinizing and follicle-stimulating hormones that are needed for the production of testosterone hormones in the body.

Most Awesome Attribute:

Clomid is a proven estrogen blocker in its own right and has been seen to help reduce the amounts of this female hormone when used properly and in a regular basis.

The Downsides:

Compared to other SERM’s that are available commercially nowadays like Toremifene and Nolvadex, Clomid is slightly less potent in terms of lowering estrogen levels. You’ll need to use more of it to get the results you’re looking for. Here are also a few side effects of using Clomid:

  • Restlessness and sleeping issues
  • Mild sensitivity of the eyes to light
  • Blurred vision
  • Bloating
  • Pelvic or stomach pain

Best SERM Pick #2: Toremifene

Toremifene (also known as Torem-Fareston) is a non-steroidal anti-estrogen SERM that was originally developed to treat metastatic breast cancer – meaning it has already spread to other parts of the body – among postmenopausal women. Most types of breast cancer usually start during menopause and require a certain amount of estrogen to really develop.

Most Awesome Attribute:

Based on clinical tests and feedback from bodybuilders who have already given Toremifene a go, what gives this SERM an edge compared to its counterparts is its ability to produce higher lipid values when used properly.

The Downsides:

Toremifene is a bit more expensive than other selective estrogen receptor modulators, particularly when its price tag is compared to Tamoxifen, a similar SERM. Based on user feedback, the following are its side effects:

  • Increased urination
  • Mild limb swellings
  • Having occasional sensations of spinning and dizziness
  • Increased sweating
  • Sudden episodes of exhaustion
  • Itching and discoloration of the skin

Best SERM Pick #1: Tamoxifen or Nolvadex

Tamoxifen or more popularly known by its generic name, Nolvadex, is perhaps the strongest SERM ever formulated.

Apart from having the ability to block the actions of estrogen in the body, it has also been seen to be very effective when it comes to not just slowing and even stopping breast cancer from spreading, but also significantly lowering its risk among men and women who are at higher-than-average risk for the disease.

Most Awesome Attribute:

Compared to Clomid and Toremifene, Nolvadex is the strongest and most potent of the bunch. This simply means that your chances of achieving your PCT goals when you’re using it are going to be much higher.

The Downsides:

However, akin to its counterparts, Nolvadex also has the following few side effects when you use it when you’re having your post cycle therapy:

  • Nausea
  • Temporary loss of sexual interest and ability
  • Muscle aches and cramps
  • Thinning of hair (Check out Infinity Hair for a great solution)
  • Mild headaches
  • Numbness or tingling of the skin

Something You Need to Take Note Of

Using a particular SERM during post cycle therapy is a different experience for each and every user. What's effective for one may not be as potent for others. Keep in mind to use a SERM only in recommended doses to get positive results when you're on them.

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