The History & Background of 11-Ketotestosterone
11-Ketotestosterone is somewhat similar to the hormone testosterone but is a naturally occurring compound as the primary androgen in fish. It is broadly distributed throughout the animal kingdom and the food support. It does not convert to estrogen even if it has potent anabolic activity. 11-Ketotestosterone is also known to lower cortisol in the body which is associated with high levels of fat most especially around the stomach. XI-KT in a supplement increase fat loss, build muscle and boost strength with ease.
StarChem Labs first released an oral product, 11-ketotestosterone back in 2008. It was sold as the active ingredient in 11-KT, a topical product by Prototype Nutrition in 2010. Another topical 11-ketotestosterone product was released in October 2013 by Iron Legion called XI-KT.
Use in Supplements
11-ketotestosterone works on two different fronts simultaneously to blitz troublesome fat reserves and puts the body into anabolic overdrive. It is a naturally-occurring anabolic compound that is found in trace amounts in humans as a metabolite of adrenal hormones and is also the primary androgen in fish which makes it present to food supply. It is active without conversion, is not capable of aromatization, and as strongly as testosterone, it activates androgen receptor. It reduces cortisol levels in fat issue and in the liver because it a strong and selective inhibitor of the reductase activity of 11β-HSD1. High levels of cortisols in those tissues are associated with a number of symptoms of metabolic syndrome, like increased hepatic glucose production, adipocyte differentiation, central obesity, and resistance of insulin. It aids in the cutting process and helps with fat loss while retaining strength and muscle. It is suited as a “recomp” agent for simultaneous fat loss and muscle and gaining of strength.This is perfect for both beginners and experienced bodybuilders and is also best for cutting cycles. KT-11 can help add on tons of new muscles and will burn off excess fats quickly making the muscles look thick in a perfect and neat look.
This ingredient is very potent on its own but can also make a great addition to a cutting cycle in which a person desires to lose fat and reduce cortisol. In some countries where it is considered legal, it is a decent stack item that helps overall quality of the mass from a standard cycle of other steroid. For oral, a typical dose should be 200-300 mg while a half of this for a transdermal per day. For the use of injectable, it is best combined with an ester for a dosage of 400 mg a week along with other cutting steroids, Anavar or Masteron for example.
Products Containing 11-Ketotestosterone
|#3: Prototype Nutrition: 11 KT Spray
Contains: 240 mL
AVG Review: NONE
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|The 11 KT spray gets its name from its key ingredient the 11-ketotestosterone it is a natural adrenal hormone produced in all mammals including humans. This will give you increases in both strength and muscle, but avoids some of the negative side effects associated with strong suppressive prohormones.
|#2: 11-X BY LGI SUPPLEMENTS
Contains: 75 capsules
AVG Review: NONE
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|The 11-X by LGI has the ability to help lower your cortisol levels. Cortisol is a hormone that causes your testosterone levels to get low, your muscles to breakdown and promotes fat gain. Lowering this and you get the complete opposite! More Testosterone! More Muscle! Less Fat!|
|#1: ICON 11
Contains: 30 mL
AVG Review: NONE
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|The ICON 11 has pure 11-ketotestosterone delivered topically with an advanced transdermal delivery system to boost bio-availability to unbelievable levels. The 11-ketotestosterone is the target hormone of 11-OXO and is a naturally-occurring highly anabolic active compound. Icon 11 exerts its highly anabolic effects to give users an increased muscle mass and strength while drastically lowering body fat for a leaner perfect physique.|
Potential Side Effects of 11-Ketotestosterone
Since it is already a metabolite of testosterone, 11-ketotestosterone is fairly metabolically resistant. It isn’t able to convert into estrogen or DHT. It has a very limited side effect profile which makes it good for those who doesn’t to experience side effects that include hair loss and estrogenic issues. It is also not methylated which is why it doesn’t cause liver stress whether whether injected or in an oral process of intake. 11-ketotestosterone has a very easy to manage side effect profile, makint it one of the safest steroids that one could use.
Is 11-KT legal?
Here is the big question…is 11-KT legal in the US? The quick and dirty answer is “No” because while it satisfies DSHEA (the FDA law) it does not satisfy DASCA since it likely has anabolic and androgenic activity and is not exempted. Thus, it is a big risk to purchase and sell 11-KT. Some companies are selling this as a transdermal and that is even more dangerous since transdermal products don’t satisfy either law.
Is the topical one supposed to be for spot fat reduction?
No I think topical one is solely to be able to have a completely saturated solution, more concentrated than the pill version and to avoid any toxicity. I thought actual spot reduction could not occur in general.
If this stuff is androgenic, then it will most likely have a negative effect on the HPTA and shut you down. What are you taking it for?
Nah it's probably not as harsh as tren or something like that from what I've read it actually helps with libido since it isn't as toxic as others. I mean obviously with a username like yours you'll understand, I'm taking it for fun.
11-ketotestosterone as a potent androgen is produced by male fishes in addition to testosterone. In a previous experiment, a juvenile African catfish (Clarias gariepinus) showed that not testosterone but 11-ketotestosterone stimulated spermatogenesis. Testosterone on the other hand, accelerated pituitary gonadotroph development.
The details of 11-ketotestosterone’s synthesis are still unknown for humans. Clarification of the production and properties off 11-ketotestosterone in humans is the main objective of this study. Human gonads were investigated for the expression of cytochrome P450 and 11beta-hydroxysteroid dehydrogenase types 1 and 2 which are the key enzymes involved in the synthesis of 11-ketotestosterone. The production of 11-ketotestosterone was investigated in Leydig cells. From 10 women and 10 men of reproductive age, plasma concentrations of testosterone were measured. Breast cancer-derived MCF-7 cells were used in the investigation of its properties. The final results indicated that 11-ketotestosterone is produced in gonads and it represents a major androgen in humans and can potentially serve as a nonaromatizable androgen.
Another study showed that higher levels off 11beta-HSD1 expression were associated with lower muscle strength in older men. 11-ketotestosterone being an inhibitor of 11beta-HSD1, 11-KT could potentially prevent or even reverse age induced loss of muscle strength. Results show that with the use of 11-KT, older lifters can maintain strength or regain lost strength due to age related metabolic changes.
Final Review of 11-ketotestosterone
This ingredient is known for amazing fat loss properties. This is perfect for both starting and the more experienced ones in bodybuilding and also considered best in cutting cycles. This ingredient is best for those who want lose fat and gain strength. 11-ketotestosterone can also help bodybuilders add tons of muscles and be in the best shape they can be.